The Centre is funded by Barts Charity and based within Queen Mary University of London at the Whitechapel campus.
The centre team (pictured above) will focus on improving the health of mothers and babies in East London, addressing healthcare challenges such as diabetes, obesity and heavy blood loss during childbirth.
The first BARC study is set to start in January 2018 – “EMmY: Effectiveness and acceptability of myo-inositol nutritional supplement in the prevention of gestational diabetes: a pilot placebo controlled double blind randomised trial”.
EmMY will aim to randomise 200 women who are at risk of developing gestational diabetes, across three sites (Barts Health, Guy’s and St Thomas’, and Central Manchester University NHS Trusts).
Participants will be randomised to receive either 4g of Myo-inositol – a naturally occurring substance produced in the human body that belongs to the vitamin B complex group – or placebo study supplement daily, from the end of the first trimester until delivery.
The pilot will examine rates of recruitment and randomisation to the trial, and rates of adherence to the intervention. Researchers will analyse reasons for participation, non-participation, and non-adherence to the trial protocol. Any preliminary estimates and insight into trial procedures from the EMmY study will then inform a future large-scale trial.
The CLAHRC is supporting the study by providing health economic analysis for the pilot and full trial and assisting with patient and public involvement..
Islington Council, Islington Clinical Commissioning Group, North East London Commissioning Support Unit, and the CLAHRC, have been granted an award for a project which aims to create a linked data-set between NHS and a local government data for households across Islington.
Local authorities hold data on their residents in terms of social care, housing, early years settings, education and crime. All of these are important to health: and in turn affected by health.
Linking local government information with health data offers an opportunity to better understand the local population’s combined health and social needs and to improve health and wellbeing in the widest sense across the Borough.
We would be able to answer questions such as:
What are local pattern of health and social risk factors for homelessness at a household level?
How could we best target prevention services and support to households at high risk of homelessness?
CLAHRC North Thames PhD Marissa Mes enjoyed success at the prestigious Annual Scientific Meeting (ASM) of the Asthma UK Centre for Applied Research (AUK CAR).
Marissa won best poster presentation when she showcased her work to delegates during the conference (below) – her research focus is assessing whether pharmacists are a suitable delivery channel for an intervention aimed at asthma patients to improve their adherence to preventer inhalers.
Our congratulations to Marissa on her prize.
Marissa’s fellow CLAHRC PhD Caroline Katzer, who is developing and evaluating an intervention to improve adherence to inhaled corticosteroids (ICS) in adult asthma patients also showcased her work at the conference via both a poster and an oral presentation, which generated a lot of discussion, and was among those complimented on the quality of her presentations.
Both PhDs are funded by the CLAHRC and affiliated to AUKCAR.
A new piece in Open Access Governmenthighlights the scale and scope of the work of our funder the National Institute for Health Research (NIHR)
In its role as the “research arm of the NHS” the NIHR’s mission is to improve both the health and wealth of the UK by means of research. A piece by Jonathan Miles (Editor, Open Access Government) gives a great overview of the work of the NIHR, and how it works with charities, industry and other sectors.
There are also a couple of examples of the groundbreaking and impactful research funded by the NIHR and the difference it is making – read the piece below.
CLAHRC researcher Dr Victoria Wood is among those presenting at an upcoming conference on “nurse specialing” – the continuous presence of a member of the nursing team for a single patient. Registration is now open for the event on Friday February 9th, hosted by our partners at University College London Hospitals NHS Foundation Trust.
Some patients admitted to hospitals may have increased confusion, delirium, and dementia or be at risk of harm from falling or leaving the ward unsafely. Other patients may present with mental health needs that require additional therapeutic care to support and maintain safety of the patient and staff and reduce risk while in hospital.
Dr Wood is one of our Embedded Research Team (ERT) based within UCLH. The ERT works closely with staff and leaders across the Trust to improve patient care and provide research evidence that staff and management can use when planning and designing services. Victoria carried out a Rapid Appraisal study of Specialling and Nurse Specials and will share her learning about the appraisal, and speak about demystifying research for NHS staff.
The end of any year sees a number of “best of” charts published and research is no exception!
We’re delighted to report that a paper produced by the CLAHRC’s Dr Werner Leber and Professor Chris Griffiths and others is 2017’s most downloaded in The Lancet HIV. Dr Werner ‘s groundbreaking work represents the first time a model to explore the cost effectiveness of screening for HIV in primary care has been applied to the UK.
The work generated great media interest (below) and offers a model to measure cost-effectiveness for commissioners and providers of HIV care.
Read the paper:
Cost-effectiveness of screening for HIV in primary care: a health economics modelling analysis
Baggaley, Rebecca F et al.
The Lancet HIV , Volume 4 , Issue 10 , e465 – e474
Our friends and colleagues at Barts Health NHS Trust are hosting some great new free training for researchers interested in involving patients and the public in their work.
New dates for 2018 have been added to this annual series of Patient and Public Involvement (PPI) workshops for researchers, funded by the Wellcome Trust, supported by UCLP and hosted by Barts Health and QMUL.
‘How to write the PPI section of a grant form’ will take place 24 January (1.30pm-4.30pm) at Charterhouse Square
‘Meaningful PPI? How was it for you?’ will take place 29 January (1pm-4pm) in Whitechapel.
CLAHRC Director Professor Rosalind Raine has been invited to be part of a major new independent inquiry considering the future of the NHS.
Professor Raine joins the Future of the NHS Commissionwhich launched on November 30th and is organised by the London School of Economics and The Lancet. It will investigate and report on options for relieving the growing pressures on the system and ensuring that the service has governance, care, operating, and funding models fit-for-purpose in the 21st Century.
Professor Raine will draw on her expertise in evaluations of NHS interventions and research experience in inequalities in the distribution of health care, its causes, impact on health inequalities and policy responses. She has long advised national, international and regional policy makers, her research being highly valued due to its diversity (spans acute & chronic conditions and all NHS settings), representativeness (national datasets, long time periods) and applied nature, allowing direct policy translation.
Calls for a rational, considered view of the NHS have come from across the political spectrum (see below) and the Commission will draw on a range of views and perspectives in its work. In April 2017 The Lancet argued that “An independent inquiry is needed to bring together clinical and policy experts, and the voices of the public and patients, to answer the question: what sort of NHS do we want and need in 2020, 2025, and 2030?”
CLAHRC behaviour change researchers and PhDs Caroline Katzer and Marissa Mes were a big hit at the recent in ESPACOMP conference in Budapest Hungary. Caroline and Marissa presented to an audience of clinicians and allied health professionals interested in adherence
ESPACOMP (European Society for Patient Adherence, COMpliance and Persistence) promotes science concerned with the assessment of what patients do with medicines they have been prescribed – and the implications when they adhere, or don’t adhere to them. Their 2017 conference brought together behaviour change practitioners and researchers from across the world and both Marissa and Caroline’s presentation generated much interest and a host of questions from the audience.
Dr Chiara De Poli presented projections of the likely impact of the various interventions currently being used to prevent diabetes across England.
Dr Esther Kwong presented her work exploring the potential for patient reported outcomes measures (PROMs) – patient questionnaires used to measure measures health gain in patients undergoing a number of surgeries – to be used when patients were admitted as an emergency.
Jennifer Martin presented her work on participatory learning and action cycle in resource-limited settings.
Impact of interventions to prevent diabetes in England: a simulation model